Gastric ulcer disease causes, signs and symptoms and treatment
What is gastric ulcer ?
Gastric ulcer disease causes, signs and symptoms and treatment Ulcer most commonly in the antrum or at the antral-fundal Junction.
Causes
- Deficient gastric mucosal barrier
- It may be infected by helicobacter pylori
- Excessive use of NSAID, Steroid or other relative use or drug.
Sign and symptoms
- Pain- it is less localised
- Pain in in left subcostal region
- Nactural pain
- Food intake may induce the pain
- Weight loss.
Diagnosis
- Elevated serum gastrin levels
- Androscopy
- Helicobacter pylori test
Treatment
Treatment by medicine is similar like PUD. It is very important to eradicate the Helicobacter pylori at first.
Use antibiotics combination
Clarithromycin 500 mg once daily for 7 to 10 days with amoxicillin 500 mg three times daily.
With co-admistration acid suppression drugs… like H2 receptor blocker drugs (eg. famotidine or Nizatidine.) or PPI ( eg. esomeprazole pantoprazole or lansoprazole) and antacid preparetion.
Sucralfate
- 1g 4 times per day 4- 8 weeks
- Drugs should use at least 2 hours before meal.
If if NSAID cannot omite with treatment regiment, it should better to choose alter the admistrasion route .
Dose adjustment
Nizatidine
150 mg two times daily for 4 weeks 30 minutes before the meal, then once daily at night for two weeks, if symptoms not relief extend the the treatment time for two weeks.
Famotidine
20 mg two times daily for 4 weeks 30 minutes before the meal, then once daily at night for two weeks, if symptoms not relief extend the the treatment time for two weeks.
PPI ( Proton Pump Inhibitor)
Esomeprazole 20 mg or prantoprazole 40 mg may be given 2 times a day 30 minutes before of meal for 3 weeks. Last 1 weeks once a day at night before the 30 minutes of meal. Dexlansoprazole is better to use 30 mg 1 or 2 times a day for 4 weeks. First 20 days 2 times a day 30 minutes before the meal and then 10 days a single dose for withdrawing the drug at night before the 30 minutes of meal.
With added a antacid preparation (eg. aluminium hydroxide and magnesium hydroxide) 1-1.5 hours after meal .
Advice
It is very important for all gastritis,Peptic ulcer disease, duodenal ulcer disease , gastroesophageal reflux disease, gastric ulcer disease patients .
Diet
- Patient should concern about his meal.
- Should be less spicy less oily .
- Less consume free sugar or sugar containig in food
- Try to avoid heavy fibre food
- Avoid coffee
- Alcohol
- Avoid milk
- Cigarette are prohibited strongly.
Lifestyle
Patient should obey the following guideline for better feel and withdrawal the medication .
Daily activities
- Wake up at morning 6 a.m take a glass of fresh water
- Then take100- 150 gram green papaya
- Then take breakfast at 8 a.m.
- At 11 a.m. take a sugar free toast biscuit with a glass of fresh water, then chewing a chewing gum for 40 to 50 minutes.
- Take your lunch within 2 p.m.
- At 5 p.m. take a sugar free toast biscuit with a glass of fresh water.
- Then chewing a chewing gum for 40 to 50 minutes.
- Take your dinner within 8 to 9 p.m.
- Go to bed within 10:00 to 10:30 p.m.
Note: If you suffer sever gastritis and don’t control at home you should go hospital immediately.
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Email address: mallicktarun@rocketmail.com
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